The pathological maelstrom of COVID-19 and cardiovascular disease

نویسندگان

چکیده

Coronavirus disease 2019 (COVID-19) is a consequence of infection the upper and lower respiratory tract with severe acute syndrome coronavirus 2 but often becomes systemic disease, important involvement other organs. A bidirectional relationship exists between COVID-19 cardiovascular disease. On one hand, preexisting comorbidities, in particular high prevalence risk factors such as hypertension diabetes chronic conditions predispose to biomarkers myocardial injury are frequently raised patients COVID-19, along arrhythmia heart failure. Localized thrombosis common finding lungs can also increase occurrence thrombotic events systemically. Thrombosis consequent different pathogenic mechanisms, which include endothelial dysfunction immunothrombosis. Thrombocytopenia alterations platelet function participate pro-thrombotic phenotype. Involvement system has consequences during recovery from development long COVID. Mauro Giacca Ajay M. Shah discuss most recent advances an array diseases.

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ژورنال

عنوان ژورنال: Nature Cardiovascular Research

سال: 2022

ISSN: ['2731-0590']

DOI: https://doi.org/10.1038/s44161-022-00029-5